(c) Representative Western blots of phosphorylation levels of PKCɛ substrates, PKCɛ and GAPDH for HEK293T cells transfected with constructs listed. These cells were either subjected to 5 minutes of ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in ... Feb. 4, 2025 — Researchers have ...

Stable RALY-overexpressed HEK293T cells were collected and total RNA was obtained by re-suspending and dispersing the cell pellet in complete RIP Lysis Buffer. Antibodies of RALY (ab170105, Abcam) or ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

Mar. 19, 2025 — The cells that make up the walls of the finest of all lymphatic vessels have a lobate, oak leaf-like shape that makes them particularly resilient to changes in fluid volume.

T cells are white blood cells that are important for adaptive immunity. They have unique cell surface receptors that are generated by randomly assorting genes. These receptors allow T cells to ...

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

相关研究成果发表在《Cell Death》上。 研究人员开展了一系列实验，运用多种关键技术方法。在细胞实验方面，他们培养了多种 CML（如 KCL22、KU812 等）、AML（如 TF1、HEL 等）细胞系以及 HEK293T 细胞，并收集了 CML 患者的血液样本 。利用基因编辑技术，构建了 PTBP2 ...