The variable expressivity of HFE-HH is related to sex and dietary factors; however, other mutations, and environmental factors such as steatosis and viral hepatitis may also contribute to clinical ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

Mar. 10, 2025 — Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in ...

Genetic engineering is the act of modifying the genetic makeup of an organism. Modifications can be generated by methods such as gene targeting, nuclear transplantation, transfection of synthetic ...

Despite insufficient evidence to support direct-to-consumer genetic testing in routine clinical care, cardiovascular clinicians increasingly face questions about its utility and interpretation because ...

Chromosomal-level aphid genome comparisons provide new insights into chromosomal evolutionary patterns and detoxification gene families evolution in aphids, aiding the understanding of species ...