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Hepatocyte death (apoptosis, pyroptosis ... Bcl-2: B-cell lymphoma-2; Bcl-XL: B-cell lymphoma-extra large; CDKN: cyclin-dependent kinase inhibitor; ER: endoplasmic reticulum; HIF-1a: hypoxia-inducible ...

Figure 1- figure supplement 3. HIF motif densities surrounding the ATAC-seq peaks. HIF-1a (A), HIF-2a (B) and HIF-1b (C) motif densities around ATAC-seq open chromatin regions (±1000 bp) by categories ...

Fang et al. find that in cell line models of TNBC, STAMBPL1 promotes expression of the transcription factor HIF-1a and its downstream target VEGF, with the consequence of stimulating neo-angiogenesis ...

这篇综述聚焦慢性脑灌注不足（CCH）引发的血管性痴呆（VaD），探讨缺氧诱导因子 1α（HIF-1α）的双重作用。HIF-1α 早期可通过 VEGF 信号促血管生成发挥神经保护作用，但长期激活会引发氧化应激等不良影响。深入研究其机制对治疗 VaD 意义重大。 慢性脑灌注不足 ...

*-Split conference with 2A schools — 1-seeds must have an overall win percentage of .500 or better OR finish in the top three in the conference standings to be seeded with the 1-seeds, or else be ...

INVESTIGATORS AND CLINICIANS anticipate that the next wave of therapeutic approaches in renal cell carcinoma (RCC) will target hypoxia-inducible factor-2 (HIF-2), a transcription factor that is ...

West Perth have signed a new sponsorship deal at its Joondalup venue. The Falcons’ home ground will be known as HIF Health Insurance Oval in a three-year deal, which will include HIF-sponsored ...

District 6 dynamo Bishop Guilfoyle is back in Hershey trying to win its second straight PIAA 1A girls basketball title. In the way is two-time District 3 champ Linville Hill Christian. The two ...

State-run HAL is procuring the engines to power the Mk-1A variant of the Tejas jets. In February 2021, the defence ministry sealed a Rs 48,000 crore deal with HAL for the procurement of 83 Tejas ...