HIV-1 Vif induces a unique and prolonged pseudo-metaphase arrest by disrupting phosphatase feedback regulation at the kinetochore.

HIV replication is linked to cellular gene transcription and requires target cell activation. Therefore, should an activated, infected cell become transcriptionally inactive prior to cytopathic ...

For the first time, the CRISPR-Cas9 gene editing system has been successfully employed to cut HIV out of infected cells. The researchers hope this could one day lead to treatment that renders ...

Researchers are therefore exploring other ways to protect cells from HIV, including using CRISPR gene editing to disable or delete CCR5 receptors on immune cells. But there is an urgent need for ...

In August 23 Cell, Astrid Schröder and colleagues at The Salk Institute, La Jolla, California show that HIV-1 chooses active genes and local hotspots for integration in the human genome (Cell 2002, ...

Dolutegravir plus lamivudine demonstrates noninferiority to the standard-of-care three-drug regimen in treatment-naive patients with HIV without preliminary drug resistance testing. Researchers ...

At this point HIV has become AIDS ... Each chromosome contains short sections of DNA called genes. These genes carry the instructions that determine features, such as eye colour, hair colour ...