HIV Gp120 (308 - 331) 是一段线性多肽片段，由 24 个氨基酸残基组成。其氨基酸序列中包含多个带电荷和极性的氨基酸，如精氨酸（Arg）、赖氨酸（Lys）等，也有疏水性氨基酸如苯丙氨酸（Phe）、缬氨酸（Val）等 。这些不同性质的氨基酸通过肽键连接在一起 ...

多种 HIV 蛋白可在 HAND 进展过程中激活炎性小体，如 HIV gp120 蛋白诱导小胶质细胞释放 IL-1 β，其诱导的神经炎症和神经病理依赖于 NLRP3 炎性小体激活和下游焦亡及 IL-1 β 产生；HIV gp120 还诱导嘌呤能 2×4（P2×4）受体表达，触发 NLRP1 炎性小体激活；HIV-1 辅助病毒 ...

The CDC represents 91% of all HIV prevention funding. Eliminating these programs would have a significant impact on the prevention and treatment of this virus in the US. Amidst ongoing job and ...

A six-monthly injection to reduce the risk of HIV transmission is being offered to sexually active women in parts of England as part of a new clinical study. The study will be carried out in ...

Millions in federal funding — supported by Democratic and Republican leadership alike ― had helped buoy a swath of programs and research into new injectable drugs for HIV prevention and treatment, ...

An additional 124 institutions are in blue states. Sybil Hosek, a research professor at the University of Illinois-Chicago, helps run a network that focuses on improving care for people 13 to 24 years ...

Dozens of HIV/AIDS activists on Thursday gathered in front of the State Department and demanded the Trump-Vance administration fully restore President’s Emergency Plan for AIDS Relief funding.

Public health initiatives aimed at HIV/AIDS prevention would no longer exist. Major parts of the National Institutes of Health would be abolished. The Food and Drug Administration would cease ...

A report released this week by Harris County Public Health found that the Houston area has a higher rate of HIV and other sexually transmitted infections compared to the Texas average. According ...

HOUSTON — A new report from Harris County Health shows cases of HIV and other sexually transmitted infections are rising throughout the Houston area at a faster rate than any other place in Texas.

Over four decades since its discovery, human immunodeficiency virus (HIV) remains one of the most challenging infectious diseases. Antiretroviral therapy (ART) has turned HIV from a fatal diagnosis ...

Introduction: While HIV-1 subtype C (HIV-1C) is the most prevalent and widely distributed subtype in the HIV pandemic, nearly all current prevention and therapeutic strategies are based on work with ...