and the structural basis for the neutralization differences between laboratory-adapted and primary HIV strains. Thus the first look inside the gp120 envelope has proven most revealing. As with all ...
When HIV is exposed to CBAs, virus escape eventually occurs predominantly by deleting its glycans on the viral envelope glycoprotein gp120. It has been shown that such mutant virus strains have an ...
Determinants of HIV cell tropism & chemokine receptor usage The V3 loop of HIV-1 gp120 is a primary determinant of cell tropism and chemokine receptor usage, whereas the V1/V2 region is involved ...
N6LS (also known as VH3810109) targets the gp120 protein on HIV’s surface, which the virus uses to bind to CD4 T cells. In the previous phase I SPAN study, ViiV researchers showed that N6LS had a ...
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