Without CD4 T helper cells, the immune system cannot recognize and coordinate a defensive response to diseases like HIV. This is when a person is said to be immunocompromised. During maturation, ...

And people with HIV do not always have AIDS. HIV is the virus that’s passed from person to person. Over time, HIV destroys an important kind of the cell in your immune system (called CD4 cells or T ...

Suppressor T cells then "turn off" CD4 activity when a sufficient immune response has been achieved. A CD4/CD8 ratio is considered normal when the value is between 1.0 and 3.0. When a person is ...

T cells are white blood cells that are important for adaptive immunity. They have unique cell surface receptors that are generated by randomly assorting genes. These receptors allow T cells to ...

At the data cutoff, 78% of patients were still in complete molecular remission. The combination of dasatinib and sequential anti-CD19 and anti-CD22 chimeric antigen receptor (CAR) T-cell therapies ...

Benjamin Chen, MD, PhD, of the Icahn School of Medicine at Mount Sinai, discusses the implications of his new study involving genetically tagging immune cells with latent HIV. Yeah, my pleasure.

Poor physical performance in patients with non-Hodgkin lymphoma receiving CAR T-cell therapy was linked to worse survival and increased risk of neurotoxicity in a cohort study.

Yescarta – a CD19-directed genetically modified autologous T-cell immunotherapy investigated in the ZUMA-1 trial – is the first chimeric antigen receptor (CAR) T-cell therapy recommended for ...

This comparison was easy to make because some of these animal viruses and HIV shared biological infectious processes, such as the induction of syncytia ... Isolation of T-cell tropic HTLV-III ...

The functions of HIV-specific CD8 + T cells are better preserved in LTNPs and elite controllers as compared with noncontrollers. Targeting of the HIV-1 Gag protein and the breadth of Gag-specific ...

HIV without proactive attention can quickly spread widely and gets out of control fast. We learned that in the 1980s and the 1990s, and we don't want to go back to that time. What we're doing in ...