This study investigated the role of AIM2 in pyroptosis within proximal tubular epithelial cells in DN. We observed significantly elevated AIM2 expression in renal tubules from DN patients and db/db ...

Knockout of STING in DLBCL cell lines leads to increased mitochondria membrane potential (MMP) and ATP generation, and decreased apoptosis. Mechanistically, STING inhibits hexokinase II (HK2) to ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in ... How Healthy Stem Cells Turn Into Or ...

结果发现 STING 通过 HK2 / 乳酸 / IFN-γ 轴影响 CD8? T 细胞功能和记忆分化 ... 为了揭开这座 “神秘岛屿” 的面纱，东南大学医学院和金陵医院等单位的研究人员在《Cell Communication and Signaling》期刊上发表了题为 “Intrinsic STING of CD8 + T cells regulates self-metabolic ...

这项重要的研究成果发表在了《Cell Reports》期刊上。 为了开展这项研究 ... 在研究结论和讨论部分，研究人员指出，他们发现的 HK2/glycolysis/H3K18la 正反馈环在 MASLD 的发展中起到了关键作用，阻断这个环可以有效减轻疾病症状。这一发现揭示了 MASLD 发病过程 ...

Your body is made of cells -- trillions of them. Cells are the basic building blocks of people and all other living things. Researchers study them to learn more about health and diseases.

You can increase white blood cells (WBCs) by taking certain medications and eating immune-boosting foods, like yogurt, lean protein foods, antioxidant-rich vegetables, and more. Maintaining a normal ...

Mar. 12, 2025 — A new study analyzing diet, average plasma sugar levels and cancer prevalence in some 273 vertebrate species showed surprising results. The study found no significant link ...

Liver fibrosis is a major global health concern, developing as a result of chronic liver diseases (CLDs) such as viral ...

Whole-body and SPECT/CT scans confirmed accumulation of the hK2-targeting antibody to prostate cancer tumors in patients with mCRPC, and radioligand therapy, T-cell engager, and CAR-T cell therapies ...

Cell biology is the discipline of biological sciences that studies the structure, physiology, growth, reproduction and death of cells. Research in cell biology uses microscopic and molecular tools ...