1 The College of Life Sciences, Northwest University, Xi’an, Shaanxi, China 2 Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi’an, Shaanxi, China High-mobility group ...

Using a murine model of HS, the role of high-mobility group box 1 (HMGB1)-receptor for advanced glycation end products (RAGE) signalling in regulation of ILC2 proliferation, survival and function was ...

结果发现 NMN 通过激活 H4K16ac-Hmgb1-Fyn-PLD 信号通路促进 FGSC 增殖，为生殖医学提供了新的治疗靶点。 在生命的长河中，生育是延续人类种族的关键环节，而女性的生殖健康则在其中扮演着至关重要的角色。近年来，不孕不育的发生率不断攀升，这一现象引发了 ...

Although the benefit/risk of therapeutic inhibition of VSMC proliferation in atherosclerosis is unclear, experimental and human evidence strongly suggests the therapeutic potential of ...

Department of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai 200040, P. R. China Institutes of Integrative Medicine, Fudan University, Shanghai ...

University of Illinois at Chicago, Chicago, IL.

在 U87MG 细胞中，过表达 PHGDH 能调节多个基因的表达，且该调节作用依赖于其核定位，而非酶活性。 PHGDH 调节 IKKα 和 HMGB1 表达：通过整合多种数据分析，确定 IKKα 和 HMGB1 为 PHGDH 的潜在转录靶基因。在 U87MG 细胞和 BOs 中，PHGDH 能激活 IKKα 和 HMGB1 的启动子 ...

The authors do not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and have disclosed no relevant affiliations beyond ...