This work reports that the extended N-terminus of the budding yeast centromeric histone, Cse4, stabilizes its localization at centromeres via binding to at least two kinetochore proteins. The Cse4 ...

2021) also showed its effects on male reproductive health with significantly altered DNA methylation, histone H3 lysine 27 trimethylation (H3K27me3 ... and Goat Anti-Rabbit IgG H&L (1:100; Abcam, ...

histone methylation in particular, covers a pivotal role being involved, among others, in fine tuning of cell proliferation and differentiation, mediated by specific controls of transcriptional ...

We found that nuclear DLEU2 directly binds HBx and the histone methyltransferase enhancer of zeste homolog 2 (EZH2), the catalytic ... HBx and DLEU2 modulates transcription from the HBV covalently ...

The most popular of these treatments aim to alter either DNA methylation or histone acetylation. Inhibitors of DNA methylation can reactivate genes that have been silenced. Two examples of these ...

DNA is often compared to a written language. The metaphor leaps out: Like letters of the alphabet, molecules (the nucleotide bases A, T, C and G, for adenine, thymine, cytosine and guanine) are ...

Learning about your genetics and ancestry is easier than ever. All you need to do is choose from the many DNA ancestry tests available online, receive your kit and send back the required DNA samples.

Dopamine, serotonin, and histamine carry messages between neurons. They can also influence circadian gene expression ...

Histone post-translational modifications are ... transcription activators on both chromatinized and nonchromatinized DNA templates. Fan, Shang, Song, Chen et al. identify the Integrator–PP2A ...

Comparison of that ancient DNA with modern human DNA showed that the two species had interbred and that people today still carry the genetic fingerprint of that intermixing. Since then ...