Despite its significant global burden, the underlying mechanisms of immune dysfunction in sepsis remain incompletely understood. This study explores the role of DNA methylation in white blood cells in ...

Cullin 4B (CUL4B), a pivotal member of the Cullins protein family, plays a crucial role in immune regulation and has garnered significant research attention. CUL4B, through the Cullin 4B-RING E3 ...

招募染色质调控蛋白：该修饰位点能特异性招募含有特定结构域（如异染色质蛋白 1，HP1，其含有色域结构域可识别 H3K9me3）的染色质调控蛋白。这些蛋白进一步促进染色质的压缩和沉默状态的维持，通过形成高阶染色质结构，限制基因的可及性，从而调控基因 ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The structure of chromatin at the nucleosome ...

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