PEG-Naloxol (NKTR-118) in Phase II clinical trials. Clinical benefit has already been demonstrated with polymer–drug conjugates bearing classical chemotherapeutic agents. The future of cancer ...
Polymers are either natural or synthetic macromolecules composed of many repeating units (monomers) usually arranged in the form of a chain. Examples of polymers are silk, rubber, silicone, DNA ...
Polymer synthesis, also called polymerization, is the process by which monomers (small molecules) are covalently bonded to form a (usually long) polymer chain or network. Well-defined vinyl ...
The first includes polymeric carriers that use covalent chemistry for direct drug conjugation (e.g., linear polymers). The second group includes hydrophobic interactions between drugs and ...
Department of Biological Science and Technology, Center for Intelligent Drug Systems and Smart Bio-devices (IDS 2 B), National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan Department of ...
Hubei Key Laboratory of Genetic Regulation & Integrative Biology, Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, School of Life Sciences, Central China Normal University, ...