To rule out possible artifacts associated with the use of Jurkat T cells, we also examined the responses of purified human peripheral T cells to APCs expressing membrane-tethered OKT3 anti-CD3 scFv.
Specificity also entails recognition of and selective activity towards particular ubiquitin chain types, at least eight of which are now known to coexist in yeast and mammalian cells. DUBs might ...