Epidermal growth factor receptor (EGFR) is a major oncogenic protein, and thus EGFR-targeting therapies are widely used in patients with various types of cancer, including lung cancer. However, ...
In summary, we demonstrate the development of a novel alveolar organoid model and use it to identify effectors of SFTPC maturation ... which can self-renew and differentiate to alveolar type 1 cells, ...
Disorders of surfactant protein biology cause dysfunction of alveolar type 2 cells and can lead to interstitial lung disease. This study describes the development of genetically manipulable, mature ...
"Using a computerised model for analysing the deposition, the study revealed that more nanoparticles are deposited in the alveolar regions of the human lungs. Because these nanoparticles are about ...
Signet’s organoid models, derived from real-world cancer genomics data, can closely mimic human biology in 3D tissues to identify novel targets and evaluate drug efficacy with greater clinical ...
Human rhinoviruses (HRV), the primary ... has dedicated seven years to establishing the world's first respiratory organoid culture system using lung adult stem cells and nasal epithelial cells.
When Homo sapiens appeared some 300,000 years ago, at least six other human species already shared the planet. Here, in the studio of paleoartist John Gurche, are model representations of those ...
Signet’s organoid models, derived from real-world cancer genomics data, can closely mimic human biology in 3D tissues to identify novel targets and evaluate drug efficacy with greater clinical ...
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract that affects an estimated 2.4 to 3.1 million people in the US alone. Despite decades of research, ...
On January 14, hippies and other counterculture participants swarmed to the polo grounds in San Francisco’s Golden Gate Park in a gathering called the Human Be-In. Timothy Leary advised ...