IFN-α2 (in most centers today pegylated IFN-α2 [Peg-IFN-α2]) induces major or complete molecular remissions in a subset of JAK2V617-positive patients with essential thrombocythemia (ET) and ...
JAK/STAT, and T-bet. In PD-1/PD-L1 immune checkpoint inhibitor cancer treatment, IFN-γ is a prognostic marker. The production of IFN-γ is associated with an improved response to immune ...
For example, activated T helper type 1 lymphocytes secrete interferon (IFN)-γ, which has potent effects on osteoclastogenesis in vivo and in vitro. IFN-γ, however, is known to cause both bone ...
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