One key factor in this evasion is the disruption of dendritic cell (DC)-mediated immune mechanisms ... Overall, studies confirm significant reductions in conventional and pDCs in MM patients. These ...

The study, published in Nature Communications, shows that a specific subtype of immune cell—type I dendritic ...

Without NF-κB p65, dendritic cells get stuck in an immature state and cannot promote T cells to fight the infection. In contrast, dengue virus really stimulates dendritic cells to make lots of ...

BPDCN is an aggressive type of blood cancer that originates from plasmacytoid dendritic cells (pDCs), a component of the immune system that produces type 1 interferon cytokines. These cytokines ...

Called "tolerogenic dendritic cells," these cells enable food to pass through the body without triggering an immune reaction, unless they malfunction to cause allergies. The cells were also found ...

IFN-γ ELISpot-positive neoantigen peptide-pulsed dendritic cell. Monocyte-derived immature DCs from a patient with recurrence (Recurrence #8) were pulsed with a long peptide (NGKKVRKNWLSSWAVLQV; ...

Dendritic cells (DCs) are critical in the maintenance of self-tolerance and altered functions of DCs have been implicated in the pathogenesis of a number of autoimmune diseases, such as rheumatoid ...

1Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia.

Duke University Medical Center, Chapel Hill, NC.