Acquisition of the constitutively active Janus kinase 2 (JAK2)V617F mutation occurs in almost all patients with polycythaemia vera (PV) and in a significant number of patients with essential ...

Create, view, and edit professional diagrams collaboratively as part of your Microsoft 365 subscription. Visio in Microsoft 365 brings core Visio capabilities to Microsoft 365 and helps you create ...

To facilitate the visualization of data models based on CIDOC CRM and its extensions when using the diagrams.net tool. diagrams.net libraries is a collection of custom shape library files (.xml) of ...

(A) Diagram of hGHR-ΔBox1 showing the deleted box 1 region in the intracellular domain of hGHR. (B) γ2A-JAK2-hPRLR cells were transfected with hGHR-ΔBox1. Transfected cells were imaged by dSTORM ...

3月17日，记者从哈尔滨医科大学附属第二医院获悉，该院于波教授和贾海波教授团队，首次证实了JAK2 V617F突变可使动脉粥样硬化斑块侵蚀发生风险增加10倍以上，并指出突变引起的中性粒细胞过度激活以及NET形成可能是斑块侵蚀风险增加的重要机制。相关研究 ...

Here, the latency reactivation capacity of a subclass of selective JAK2 inhibitors was characterized as a potential novel therapeutic strategy for HIV-1 cure. Notably, JAK2 inhibitors reversed HIV-1 ...

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Figure 1. Structure and function of the glomerulus. This diagram depicts the structure and function of glomerular endothelial cells, glomerular basement membrane, and podocytes, primarily podocytes.