Research team developed PathActMarker, a software package for pathway activity inference and analysis. It preprocesses gene ...

The process of complex diseases is closely related to the dysregulation of key biological pathways, it is crucial to identify the dysfunctional ...

Ephraim’s complaint against Gideon; kings of Midian slain; Gideon’s children; his death; Abimelech made king: death of Abimelech. And Gideon said unto them, I will not rule over you, neither shall my ...

GSEApy is a Python/Rust implementation for GSEA and wrapper for Enrichr. GSEApy can be used for RNA-seq, ChIP-seq, Microarray data. It can be used for convenient GO enrichment and to produce ...

为解决传统生物网络分析在处理不完整或异质数据集时的困境，研究人员开展基于基因集嵌入揭示潜在生物学关联的研究，发现新关联并验证跨物种稳健性，为理解复杂生物过程和疾病提供新视角。

在研究结论和讨论部分，该研究首次全面鉴定了与 AMI 中 Hippo 信号通路相关的生物标志物，包括 NAMPT、CXCL1、GIMAP6 和 GIMAP7，为开发针对 AMI 的靶向治疗提供了理论基础。尽管研究存在一定局限性，如使用的数据集在以往研究中被广泛应用、样本量相对较小等，但研究结果仍具有重要意义。这些生物标志物不仅具有临床诊断潜力，还为深入理解 AMI ...