It was found that a phospho-dead mutation at Y163 abolished the inhibitory ... In a search for the kinase responsible for PDK1 Y163 phosphorylation, TIE1 was identified as a potential candidate.

The second most common is the L528W mutation, which is often associated with resistance to covalent BTK inhibitors and is sometimes referred to as a “kinase-dead” mutation due to its impact on the ...

It was found that a phospho-dead mutation at Y163 abolished the inhibitory ... In a search for the kinase responsible for PDK1 Y163 phosphorylation, TIE1 was identified as a potential candidate.

It was found that a phospho-dead mutation at Y163 abolished the inhibitory effects of ING5 overexpression ... PDK1 Y163 phosphorylation in lung cancer progression and its potential as a therapeutic ...

Here's how to watch The Walking Dead shows in order, including spin-offs such as Daryl Dixon season 2 ...

In early December 2024, a group of researchers published an article in the journal Science, entitled "A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors".

Researchers in the group of Dr. Myriam Charpentier discovered a mutation in a gene in the legume Medicago truncatula that reprograms the signaling capacity of the plant so that it enhances ...

Department of Biology, University of Fribourg, Fribourg, Switzerland Metabolomics and Proteomics Platform (MAPP), Department of Biology, University of Fribourg, Fribourg, Switzerland ...