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SUCNR1:肝脏缺血再灌注损伤治疗的新靶点
目前,虽然人们越来越关注这一病理过程,但库普弗细胞(Kupffer cells,KCs ... 同时,Sucnr1 基因缺失抑制了 KCs 的 M1 极化,使 M1 标记物(iNOS 和 Cox - 2)和促炎细胞因子(TNF-α、IL-6 和 IL-1β)的表达降低,M2 标记物(Arg1 和 Ym1)和抗炎细胞因子(IL-10)的表达 ...
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