Cell signalling is the mechanism by which stimuli are transmitted via a signalling cascade to effector molecules that orchestrate the appropriate response. Types of cell signalling pathways ...

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Autophagosomes form at points of contact between the endoplasmic reticulum (ER) and mitochondria, and two ubiquitin-like conjugation systems (Atg12 and Atg8/LC3) extend a double-membraned ...

Depression damages neurons due to insufficient energy supply, increased oxidative stress, and activation of cell death signaling, thereby affecting emotional regulation and ... the recognition and ...

Apr. 11, 2025 — A multi-institutional team developed a chimeric antigen receptor (CAR) T cell-based strategy for specifically targeting AML cells in patients who relapsed following other treatments.

Apr. 9, 2025 — A new study has found that certain bacteria living in the nose may influence how likely someone is to get a COVID-19 infection. The research reveals ...

Long noncoding RNAs (lncRNAs) are a diverse group of transcripts with limited protein-coding capacity, which have been recognized for functional molecules for regulating cancer progression including ...

The UK has launched a £1m ($1.3m) research partnership to explore the use of limestone calcined clay cement (LC3) in nuclear waste encapsulation. The University of Sheffield, Sellafield Ltd, the ...

GTPase activity of ARF1 is dispensable for mitochondrial maintenance. STING inhibitor H-151 and amlexanox reduce chronic IFN signalling in patient fibroblasts. In this study, we present data relating ...

Those cancers begin in other types of tissue, such as: Basal cell carcinoma. This is the most common form of all cancers. It occurs in cells lining the deepest part of the skin's outer layer.

This ancient cell mechanism is thought to be critical ... autophagic responses concomitant with reductions in apoptotic signaling,” the researchers wrote in their study published in Advanced ...