AZD0780 30mg taken daily demonstrated robust, dose-dependent, placebo-adjusted reductions in LDL-C from baseline to week 12 ...
Familial hypercholesterolemia results from gene mutations approximately halving the number of functional LDL receptors in heterozygotes and a greater lack in homozygotes. Reduced receptor-mediated ...
Once processed by LPL, the VLDL becomes a VLDL remnant. The majority of the VLDL remnants are taken up by the liver via the LDL receptor, and the remaining remnant particles become IDL ...
LDL is often called “bad” cholesterol because when it accumulates in the blood, it can form plaque in the arteries, a ...
A cholesterol receptor protein called LDLR appears to be a key driver of neurotoxicity in sporadic ALS, per new research ...
Study deciphers the molecular handshake between LDL receptors and apoB100, shedding light on cholesterol metabolism and its ...
Experts recommend starting your mornings with a cup of green tea instead of milk or coffee, as green tea helps block ...