These bile-acid-controlled signalling pathways have become the source of ... cholesterol levels then induces the expression of the LDL receptor, which increases the delivery of cholesterol to ...

Much of the LDL particles are taken up by LDL receptors in the liver; the remaining LDL is removed by way of scavenger pathways at the cellular level. As LDL is taken up by receptors, free ...

How have viruses hijacked the cell's pathways to cause infections ... they observed that LDL internalization was mediated by a specific receptor present in the surface of the cells.

Familial Hypercholesterolemia "The justly celebrated unraveling of the LDL receptor pathway revealed that mutations in a single gene give rise to familial hypercholesterolemia (FH)," Peter Libby ...