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This review will focus on transcriptional, posttranscriptional, and posttranslational pathways that regulate the LDLR and its availability at the plasma membrane (Figure 1). The concept that LDL was ...
"Dyslipidemia" refers to an abnormality within the lipid profile, encompassing a variety of disorders relating to elevations in total cholesterol, LDL, or TG, or conversely, lower levels of HDL.
为探究胆固醇代谢对多发性骨髓瘤(MM)的影响及关键调控机制,研究人员开展了 MM 患者胆固醇代谢相关研究。结果发现低血清胆固醇与 MM 患者预后不良相关,LRP8 是关键调控基因,其有望成为 MM 治疗靶点,为 MM 治疗研究提供新方向。
Background: Obesity is a complex, chronic, stigmatized disease whereby abnormal or excess body fat may impair health or increase the risk of medical complications, and can reduce quality of life and ...
Stress and depression can trigger cardiovascular disease, according to recent research. They also reduce the effectiveness of ...
Pharmacology is a branch of biomedical science, encompassing clinical pharmacology, that is concerned with the effects of drugs/pharmaceuticals and other xenobiotics on living systems, as well as ...
Health specialist Dr Michael Mosley previously told the BBC: "When you eat a chilli, the capsaicin is released into your saliva and then binds on to TRPV1 receptors in your mouth and tongue.