为探究 Clusterin 在 LPS 诱导肝损伤中的作用及机制，庆熙大学研究人员开展相关研究，发现 Clusterin 可抑制 NLRP3 炎症小体和 STAT3 信号通路来保护肝脏。该研究为炎症性肝病治疗提供新靶点，值得科研读者一读。 在肝脏疾病的研究领域，炎症反应就像一个隐藏在 ...

EGT was also observed to markedly suppress the LPS-induced phosphorylation of JAK/STAT3 and NF-κB, offering a novel insight into the anti-inflammatory mechanism of EGT. Discussion: In conclusion, the ...

Our drug discovery model has identified two novel STAT3 SH2 domain inhibitors 323–1 and 323–2 (delavatine A stereoisomers) in a series of experiments. In silico computational modeling, drug affinity ...

"In the amygdala, the gene Stat3 is involved in the regulation of blood pressure and possibly plays a role in blood pressure elevation in response to chronic stress. It might also be involved in ...

School of Life Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China ...

SEE ALSO: Get the latest forecast from the Storm Alert Team All LPS activities are also canceled, the district said. LPS said it would continue to monitor the conditions for Thursday.

Our aim was thus to clarify the role of STAT3 during fetal lung development. Materials and Methods The STAT3 expression pattern was assessed by immunohistochemistry. Rat lung explants were harvested ...

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