The team at UC Davis set out to answer a difficult question: Can you keep the benefits of LSD while removing the hallucinogenic effects that make it unsafe for many patients? The researchers focused ...

To design the molecule (+)-JRT the researchers flipped the position of just two atoms in LSD’s molecular structure. The chemical flip reduced JRT’s hallucinogenic potential while maintaining ...

A cortical neuron treated with JRT, a synthetic molecule similar to the psychedelic drug LSD. Drugs like JRT might enable new treatments for conditions such as schizophrenia, without the ...