These essential enzymes maintain genome integrity and play a vital role in DNA replication and repair across all living organisms. By forming phosphodiester bonds, it ensures the seamless connection ...

Loss of this phosphorylation could result in increased single strand gaps, accelerated speed of fork progression, and eventually genomic instability. And for this process, PNKP enzyme activity is not ...

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights into viral replication mechanisms.

DNA has two strands. Each strand is a sequence of four chemical bases: adenine (A), cytosine (C), guanine (G), and thymine (T). The strands are anti-parallel and complementary. ‘Anti-parallel ...

Bathe’s lab also took the step of attaching single-strand DNA “barcodes” to the outside of each sphere. Beads containing images of a tabby cat had labels representing “cat,” “orange ...

DNA helicases are essential during DNA replication because they separate double-stranded DNA into single strands, allowing each strand to be copied. Dr Taha Shahid, from the University of ...

Apr. 2, 2025 — Jurassic dinosaurs milled about ancient Scottish lagoons, leaving up to 131 footprints at a newly discovered stomping ground on the Isle of Skye in Scotland, according to a new ...