G Protein-Coupled Receptors (GPCRs) in advancing GPCR-targeted therapies, including the use of agonists, antagonists, biased ...

Abstract: Precise quantification of protein-ligand interaction is critical in early-stage drug discovery. Artificial intelligence (AI) has gained massive popularity in this area, with deep-learning ...

Drug promiscuity can also be evaluated from the ... provided the original work is properly cited. Cite this: Targeting Ligand-gated Ion Channels in Neurology and Psychiatry: Is Pharmacological ...

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, develops and licenses biopharmaceutical assets worldwide. It offers Pradefovir, Posaconazole, Voriconazole, CAPVAXIVE, NOXAFIL ...

Among methods employed in drug discovery, pharmacophore modelling, multi-dimensional quantitative structure activity relationships (such as, 4- and 3D-QSAR), Comparative Molecular Field Analysis ...

P2Rank: Protein-ligand binding site prediction from protein structure based on machine learning.

Artificial intelligence (AI) is making significant strides in various fields, with drug discovery being one of the most impactful areas. The process of developing new drugs has traditionally been a ...

Tovecimig, formerly known as CTX-009, is a bispecific antibody that blocks the Delta-like ligand 4 and vascular endothelial growth factor A signaling pathways.