A light sheet fluorescence microscopy approach for the analysis of immune cell composition, vascularization, tissue perfusion and hypoxia enables spatial imaging of the tissue microenvironment in ...

Using the light sheet method means less damage to your sample from laser exposure, which is great for imaging delicate things like embryos, larvae, and organoids. You can use it to image alive, ...

LightSheet microscopy is a fluorescence technique that projects a thin ‘sheet’ of excitation light perpendicular to the direction of observation ... Emission signal from this volume is collected by a ...

High quantum efficiency detectors enable observations of the fastest processes at the lowest illumination light levels. The light sheet geometry illuminates only the parts of the sample you are ...

While medical centers use ultrasound daily, so far this technology is not capable of observing body tissues at the scale of cells.

The end result is data equivalent to conventional light-sheet microscopy, but requiring a single, stationary objective lens, no sample translation, and consequently very high speed 3-D imaging.

However, Dr. Daetwyler said, light-sheet microscopy comes with a significant drawback: The higher the imaging resolution, the smaller the area researchers can image. Thus, scientists have had to ...

The Zeiss LightSheet Z.1 is a stand-alone SPIM (Side Plane Illumination Microscope) capable of imaging large, living specimens at much greater speeds than more traditional confocal technology. It is ...

We are also part of Biocenter Finland Biological imaging network, and provide nationwide technology services on advanced light microscopy techniques. We belong to Euro-BioImaging Advanced Microcopy ...

something that light-based methods can't do in larger, living tissues," senior researcher David Maresca says. Key to this innovation in ultrasound imaging—a method called nonlinear sound sheet ...