LightSheet microscopy is a fluorescence technique that projects a thin ‘sheet’ of excitation light perpendicular to the direction of observation ... Emission signal from this volume is collected by a ...

Lightsheet imaging is a fluorescence microscopy technique with an intermediate optical resolution but good optical sectioning capabilities and high speed. This means that the device is best employed ...

High quantum efficiency detectors enable observations of the fastest processes at the lowest illumination light levels. The light sheet geometry illuminates only the parts of the sample you are ...

Using the light sheet method means less damage to your sample from laser exposure, which is great for imaging delicate things like embryos, larvae, and organoids. You can use it to image alive, ...

A powerful new technique combines expansion microscopy with lattice light-sheet microscopy for nanoscale imaging of fly and mouse neuronal circuits and their molecular constituents that’s roughly ...

The Zeiss LightSheet Z.1 is a stand-alone SPIM (Side Plane Illumination Microscope) capable of imaging large, living specimens at much greater speeds than more traditional confocal technology. It is ...

A wide-field imaging option facilitates sample positioning. Two Nikon CFI Plan Fluor 10x W 0.3 NA water immersion objective lenses project the light-sheet on the sample. Detection includes a high ...

However, Dr. Daetwyler said, light-sheet microscopy comes with a significant drawback: The higher the imaging resolution, the smaller the area researchers can image. Thus, scientists have had to ...