Bacteria control the homeostasis of membrane lipid biophysical properties by altering the chain length of fatty acids, as well as the ratio of saturated:unsaturated fatty acids. The de novo ...

Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, plays a pivotal role in various physiological and pathological processes. In this review, we summarize the ...

Background: Clear cell renal cell carcinoma (ccRCC), which is the most prevalent type of renal cell carcinoma, has a high mortality rate. Lipid metabolism reprogramming is a hallmark of ccRCC ...

Both the pitavastatin molecule and the lactone metabolite undergo very little metabolism by CYP3A4 and, therefore, unlike some other statins, does not interact with CYP3A4 substrates. Pitavastatin ...

After random selection, data from 1522 mother–child pairs were used in this study. Exposures and outcome measures Additive Bayesian network analysis was used to investigate the interdependency of ...

This manuscript presents a detailed characterization of male and female wildtype and Ctrp10 knockout mice, and reveals that knockout mice develop female-specific obesity that is largely uncoupled from ...

Research into selective androgen receptor modulators (SARMs) continues to evolve in laboratory settings. Ostarine and ...

Antibiotic-resistant bacteria are a serious public health threat. Understanding the biology of these bacteria—such as how ...

Antibiotic-resistant bacteria is a serious public health threat. Understanding the biology of these bacteria--such as how they synthesise their protective capsules--is essential for developing new ...

Next, we hypothesized that an oral nanoparticle-based formulation for the encapsulation of lipophilic cGAS-STING inhibitors based on lipid nanocapsules (LNCs) would represent a promising strategy for ...