The result suggests that the protein made by the gene, known as Nwd1, and other molecules it interacts with could be ...

We were puzzled that the beneficial functions of stellate cells have not been really understood." To understand the normal ...

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated with significant global public health concerns. It is prevalent in 30% of ...

Aim: The aim was to investigate mechanisms by which betaine improves hepatic insulin signaling in a dietary mouse model of insulin resistance and fatty liver. Methods: C57BL 6J mice were fed a ...

At the end of the prescribed feeding period, all mice were fasted overnight and anesthetized with an intraperitoneal injection of 1% pentobarbital sodium (50 mg/kg body weight). After anesthetization, ...

Mar. 13, 2025 — When mothers eat a diet high in fat and sugars, their unborn babies can develop liver stress that continues into early life. A new study sheds light on changes to the fetus's ...

The liver is a key at maintaining glucose and lipid homeostasis, crucial processes for metabolic health. When these processes ...

We performed confocal laser scanning microscopic analyses on the distributions of glycogen with periodic acid-Schiff (PAS) staining and serum proteins with immunostaining for mouse liver tissues.

High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in mice.

Their data showed that removing Asah1 from liver cells significantly worsened liver damage, inflammation, and fibrosis in a model of NAFLD induced by feeding mice a high-fat and high-cholesterol diet.