[5] We addressed the following research questions: How efficacious and safe is losartan, given as mono-therapy or in combination with hydrochloro-thiazide, in typical, unselected patients with a ...

Following reports linking thiazide diuretics with increased biliary cholesterol saturation, it has been postulated that these drugs increase the risk of gallstone development. Leitzmann and ...

Losartan, introduced in 1995, was the first ARB indicated for use in the treatment of hypertension. Six ARBs are currently available in the United States for hypertension: losartan, valsartan ...