Conclusions Prolonged depletion of B cells in patients with AAV after RTX therapy indicates a B-cell defect that is unmasked by RTX treatment. Our data indicate that impaired bone marrow ...

Signalling between Notch receptors and ligands influences many differentiation processes and cell-fate decisions during embryonic and postnatal development. Stem-cell maintenance, binary cell-fate ...

In the past decade there has been a growing interest in understanding sex and gender differences in myocarditis and dilated cardiomyopathy (DCM), and the purpose of this review is to provide an update ...

The cause of dysbiosis in aging and potential role of adaptive immune cells • Dysbiosis as a cause of inflammaging that upregulates myelopoiesis and downregulates lymphopoiesis in the bone marrow in ...

为探究线粒体缺陷对免疫系统的影响，研究人员以肝细胞特异性缺失 Sco1 的小鼠为模型，发现其淋巴细胞生成受损，该研究为相关疾病治疗提供新方向。 线粒体，这个在细胞中看似微小却功能强大的 “能量工厂”，不仅为细胞活动提供能量，还在维持细胞和 ...