Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged ...

The STING protein, known for helping cells fight viral infections by generating inflammation, also appears to function as a ...

Evidence suggests that in Parkinson’s disease, a breakdown in lysosomal function allows lipids to build up within cells. Variants of the GBA1 gene, the strongest genetic risk factor for sporadic PD, ...

During the endosome–lysosome transition, the compartmental pH drops, which is conducive to the function of lysosomal acid hydrolases. Here the authors show that the biological fate of rare earth ...

Kanazawa University, report in Nature Communications how the targeted suppression of lysosome function may lead to brain cancer therapy.

A new study shows that dysfunction of lysosomes can cause leakage of toxic substances within brain cells, contributing to ...