Among them, the cysteine cathepsin family plays a prominent role in the immune escape of glioma. Numerous studies have confirmed that glioma immune escape mediated by lysosomal peptidases has ...

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, but ...

The degradation of Presenilin 1 (PS1) is crucially mediated by several pathways, including the Ubiquitin-Proteasome Pathway (UPP) and the autophagy-lysosome pathway, which are vital for maintaining ...

(A) UMAP projection shows anterior and posterior LREs, as well as close cell clusters in the CV condition. Cell types are color coded. (B) Heatmap illustrates expression of lysosome KEGG pathway genes ...

This paper reports important findings on giant organelle complexes containing endosomes and lysosomes (termed endosomal-lysosomal organelles form assembly structures [ELYSAs]) present in mouse oocytes ...

Vanqua Bio, a clinical-stage biopharmaceutical company, announced that the company will present at AD/PD™ 2025 International ...

Danites take Micah’s idols and his priest, Jonathan; Danites attack Laish; moral degradation; the Levite’s concubine slain. And it came to pass in those days, when there was no king in Israel, that ...

Recently, the research team led by Professor Zhang Zhongtao and Professor Yao Hongwei from the General Surgery Center at ...

By monitoring lysosomal activity in mice with GAN ... effect where the protein cannot be degraded by its normal pathway," Opal said. "This explains why children with this disease become worse ...