肝细胞癌（HCC）治疗面临困境，现有疗法效果有限。研究人员开展了关于 L-741626 对 HCC 作用的研究。结果发现 L-741626 能抑制 HCC 进展，还可与索拉非尼协同增效。该研究为 HCC 治疗提供了新方向。

Aberrant activation of the Ras/Raf/MAPK/ERK kinase/extracellular signal-regulated kinase cascade and the VEGF pathway are commonly observed in breast cancer cells leading to malignant cell ...

Describing their results in Nature Microbiology (“ERK pathway reactivation prevents ... disrupting important MAPK pathways, and rapidly causing widespread cellular, tissue, and organ damage ...

结直肠癌（CRC）是全球第三常见的恶性肿瘤，也是癌症相关死亡的第二大原因。在确诊时，20%至25%的结直肠癌患者已出现远处转移，而在疾病进展过程中，近半数患者会发展为转移性疾病。转移性结直肠癌患者的五年生存率低于15%，而局限性疾病的五年生存率则超过 ...

Research on guinea pig embryos uncovers similarities to human embryogenesis, advancing understanding of preimplantation ...

San Diego State University, San Diego, CA.

Researchers have unlocked a powerful new way to fight solid tumors using smart immune cells that stay active longer and hit harder. Called EchoBack CAR T-cells, these new cancer-fighting tools work ...

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...