Non-genetic drug adaptation to MAPK pathway inhibitors in melanoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part 1 (Regular Abstracts); 2025 Apr ...

阿尔茨海默病（AD）临床治疗效果不佳。p38MAPK参与 AD 发病机制，针对 MAPK 的研究尝试探究其对记忆等的影响。相关 MAPK 抑制剂临床试验有积极成果，但存在问题。本文聚焦 MAPK 干预疗法治疗 AD 的临床研究，值得关注。 阿尔茨海默病现状 阿尔茨海默病（AD ...

Aberrant activation of the Ras/Raf/MAPK/ERK kinase/extracellular signal-regulated kinase cascade and the VEGF pathway are commonly observed in breast cancer cells leading to malignant cell ...

Search for other works by this author on: ...

DELFI Diagnostics, Inc., developer of innovative blood-based tests that leverage cell-free DNA (cfDNA) fragmentomics for cancer detection and monitoring, today announced its team is presenting at the ...

Simultaneously targeting lysosomal enzyme and KRAS-MAPK pathway eradicates pancreatic tumors in preclinical models 29 minutes ago Exercise boosts brain health—even when energy is low ...

Melanoma is the most serious type of skin cancer. It develops when skin cells multiply rapidly as a consequence of mutations in their DNA caused by UV exposure. Melanomas originate in the pigment ...

Cornell researchers have created a computer model that can help produce farms and food processing facilities control COVID-19 outbreaks, keep workers safe and the food chain secure. With the Food ...

mRNA specialist BioNTech has chalked up an important win in its cancer pipeline, showing efficacy with its BNT111 vaccine candidate in a phase 2 trial in advanced melanoma. The study is looking at ...

At close: April 21 at 4:00:01 PM EDT ...

The M14TIL trial involved 168 patients with stage 3c to 4 melanoma that was too advanced to be treatable with surgery, most of whom (89%) had failed earlier treatment with PD-1 inhibitors like BMS ...