在结直肠癌（CRC）治疗中，BRAFV600E突变患者预后差，BRAF 和 EGFR 抑制剂联合疗法虽有应用，但存在耐药问题。研究人员开展了关于 LSD1 抑制对 BRAF 突变型 CRC 靶向治疗影响的研究，发现抑制 LSD1 可阻断细胞谱系可塑性，有望改善患者治疗反应。

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

血小板减少症治疗手段有限。西南医科大学研究人员开展了以米替福新靶向 CCR5 治疗血小板减少症的研究。结果显示米替福新可促进巨核细胞（MK）分化和血小板生成，这为血小板减少症治疗提供了新策略。

中文名称：目前未检索到统一规范的中文名称，暂可直译为 “信号转导及转录激活因子 3 适配体”（注：适配体是一类能与特定靶分子高亲和力、高特异性结合的寡核苷酸或短肽序列） 序列相关：由于 APT STAT3 通常指针对 STAT3 的适配体，适配体序列因不同研究 ...

In addition to VVD-159642, the company is conducting other Phase I trials assessing an oral, Kelch-like, ECH-associated protein 1 (KEAP1) activator, as well as an oral signal transducer and activator ...

Head and neck squamous cell carcinoma (HNSCC) is a prevalent malignancy with high mortality, and effective treatment strategies remain limited. This study investigated the effects of benzethonium ...

Glycyrrhizin inhibits the activation of the MAPK signaling pathway in the cytoplasm ... and gorgonzine inhibited the translation of STAT3 and blocked the translation of JASC, through the upregulation ...