DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce ...

Aditxt subsidiary Pearsanta has acquired patents associated with adductomics-based DNA damage detection, to make significant advancements in cancer diagnostics. Valued at nearly $1m, the acquisition ...

A new study from Canada found that melatonin, a hormone known for its role in regulating sleep, might help reverse some of the DNA damage caused by years of poor sleep. Melatonin is produced by the ...

A team led by Prof. Wuran Wei from West China Hospital of Sichuan University and Dr. Dechao Feng from the Division of Surgery ...

The study, titled "DNA damage response regulator ATR licenses PINK1-mediated mitophagy," has been published in Nucleic Acids Research. Dr. Christian Marx, from the Wang research group, is the ...

The lesion containing DNA strand is shown in cyan; the undamaged strand is shown in blue. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-52860-y ...

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License . Mol Cancer Ther (2025) 24 (4): 497–510. Murine double minute 2 (MDM2) is an E3 ligase ...

The effect was to change an incorrect DNA letter to the right one. The result was a normal gene that functioned as it should, potentially halting liver and lung damage of patients with a rare ...

The simulations showed a lot about the complex nature of the PInC machinery.