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靶向BamB抑制菌毛组装的硝唑尼特与多粘菌素B协同抗耐药大肠杆菌 ...
针对这一困境,辽宁省教育厅重点项目的资助下,研究人员以抗寄生虫药物硝唑尼特(Nitazoxanide, NTZ)为突破口,系统探究了其通过靶向BAM复合体抑制P菌毛组装的分子机制,并揭示了其与多粘菌素B的协同抗菌效应。这项发表于《Biochimie》的研究,首次明确了BamB蛋白 ...
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