A research team has developed an innovative biomimetic dual-mode magnetic resonance imaging (MRI) nanoprobe for detecting early-stage liver fibrosis in non-alcoholic fatty liver disease (NAFLD).

Fibrosis prediction is an essential part of the assessment and management of patients with chronic liver disease. Blood-based biomarkers offer a number of advantages over the traditional standard ...

Zhang and Gu used four cohorts to examine associations between skeletal muscle strength (SMS) and chronic kidney disease (CKD) in people with metabolic dysfunction-associated steatotic liver ...

Detecting liver fibrosis early, before it becomes irreversible, is crucial for timely intervention and treatment. While MRI is a promising non-invasive tool for identifying liver fibrosis ...

At present, transient elastography and the serum marker FibroTest are the most intensively evaluated non-invasive methods for the assessment of liver fibrosis. The results of the present study for ...

Mar. 12, 2025 — Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now ...

While often asymptomatic in its early stages, the condition can lead to severe complications such as liver inflammation, fibrosis, cirrhosis, and even liver cancer if left unchecked. Non-alcoholic ...

Addressing Natural Disaster Takes Cooperation, Preparation to Ensure Patient Health ...

India faces a growing liver disease crisis linked to obesity and diabetes, affecting even non-drinkers. Experts warn that Metabolic dysfunction-associated steatotic liver disease (MASLD), driven ...

and demonstrates that disruption to the transcriptional activity of TCF7L2 exacerbates the development of dietary-induced hepatic fibrosis. Nonalcoholic fatty liver disease (NAFLD) has limited ...

In addition, expression of CDKN1A positively correlated with two clinical assessments: the disease's activity score and the fibrosis stage. In liver tissue from patients, immunofluorescence ...