A recent study has revealed how Epstein-Barr virus (EBV) intensifies ulcerative colitis (UC), a debilitating inflammatory ...

Antibodies, which recognize viruses and proteins that the body has encountered before, have long gotten most of the credit ...

Researchers from Moffitt Cancer Center have found a new way to boost cancer immunotherapy by targeting a protein called ...

With the newly completed OT-101 and IL-2 Phase 1 trial, Oncotelic is poised to begin further combination trials to determine the added efficacy of OT-101, IL-2, and CKIs in solid tumors such as lung ...

Macrophages represent one of the most prevalent cells in the colorectal cancer microenvironment ... of these cytokines and the dynamic changes in cell interactions and signaling networks in the ...

The distinct phenotypic features of inflammatory vs. wound-healing macrophages are controlled by a network of molecular pathways that relay environmental signals via signaling cascades to impact gene ...

The transition of MDMs from M1 to M2 phenotype was evaluated through gene expression and protein synthesis of M2 macrophage markers, namely scavenger receptors (CD163 and CD204), and mannose ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

Spatial transcriptomic analysis identifies epithelium-macrophage crosstalk in endometriotic lesions - (https://www.cell.com/iscience/fulltext/S2589-0042 (25)00049-5) ...

Monocyte-expressed α4β7 integrin was functionally important for dynamic adhesion to mucosal vascular addressin cell adhesion molecule 1 and in vivo gut homing. Impaired α4β7-dependent gut homing was ...