This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

"Active research and future clinical trials will give us the answer." More information: Angeles Fernandez-Gonzalez et al, ...

Identified a novel macrophage subtype in the joint and showed that these are the dominant macrophages in patients with active RA. Found this macrophage subtype is highly pro-inflammatory and ...