The study presents important findings on inositol-requiring enzyme (IRE1α) inhibition on diet-induced obesity (overnutrition) and insulin resistance where IRE1α inhibition enhances thermogenesis and ...

A new study reveals a surprising mechanism by which itaconate inhibits the active site of a peroxiredoxin enzyme to amplify redox signalling and the type I interferon response in macrophages.

Richard Staines spoke with Soren Bregenholt, the new CEO of Macrophage Pharma, about the company’s strategy encompassing both immune oncology and inflammatory diseases. In healthy tissues ...

Through CRISPR-Cas9 gene editing and single-cell analysis, they zeroed in on a gene named Zeb2.

Then, macrophages were re-integrated and further categorized into different subtypes ... revealing which cell types these programs are active in. Immune-related IFNγ and IFNα signaling, associated ...

Macrophages are involved in all stages of HS genesis through phenotypic changes ... each of which overlaps and differs in time and space (1).The formation of HS is the result of an abnormally active ...

Removing EPO signaling in mouse liver tumors leads to tumor regression along with sensitivity to immunotherapy.

Removing EPO signaling in mouse liver tumors leads to tumor regression along with sensitivity to immunotherapy.

Researchers at Children's Hospital of Philadelphia (CHOP) developed a longitudinal atlas of neuroblastoma, a common and ...

kuleuven.be Intestinal resident macrophages are at the front line of host defence at the mucosal barrier within the gastrointestinal tract and have long been known to play a crucial role in the ...

While there are plenty of excellent sports games on the Roblox platform, none of them can hold a candle to Blue Lock Rivals. It’s ripe for the Roblox treatment as one of the most popular sports ...