This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

kuleuven.be Intestinal resident macrophages are at the front line of host defence at the mucosal barrier within the gastrointestinal tract and have long been known to play a crucial role in the ...

Macrophages, a type of white blood cell, adjust their molecular signaling ... The human immune system has two lines of defense. The innate immune system acts quickly and non-specifically to ...

The human embryonic kidney cell line 293T and RAW264.7 cells were purchased from the American Type Culture Collection (ATCC, Manassas, VA, USA) and were cultured in Dulbecco’s Modified Eagle Medium ...

Research continues to highlight threats to human health with widespread chlorpyrifos use that is not assessed in current ...

1Department of Pathology, St. Jude Children’s Research Hospital, Memphis, Tennessee. Search for other works by this author on: 2Department of Computational Biology, St. Jude Children’s Research ...

How precisely mRNA vaccines train innate immune cells to shape protective host defense mechanisms remains unknown. Here we show that SARS-CoV-2 mRNA vaccination significantly establishes histone H3 ...

When your body senses something is wrong—whether it's a damaged cell or a growing tumor—it can react in many ways. One of the ...

Pulmonary sarcoidosis is a lung disease characterized by granulomas-tiny clumps of immune cells that form in response to ...