Spindle (yellow) and chromosomes (blue) in the first meiotic division of a mouse oocyte. Contributors M. Herbert, A. McDougall & H. Homer ...

Overexpression of HDAC6 in mice results in a significant thickening of the corneal epithelium. Mechanistic studies reveal that HDAC6 overexpression disrupts mitotic spindle orientation and positioning ...

Recent studies have shown that the epigenetic regulation of mRNA m 6 A modification plays an important role in gametogenesis of many species having crucial roles in meiotic initiation and progression ...

Women have a higher proportion of key immune cells between puberty and menopause, which may be linked to the sex hormone oestrogen and explain why they are less susceptible to certain infectious ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Kinesin-1-powered microtubules have emerged as versatile components in biocomputing ...

This important study reports single-nucleus multiomics-based profiling of transcriptome and chromatin accessibility of mouse XX and XY primordial germ cells (PGCs). The main conclusions of this study, ...

In this study, we confirmed the novel interactions of candidate pairs including Spindle-E (Spn-E)_Squash (Squ), by co-immunoprecipitation assay using cultured cells. In addition, a Squ mutant, which ...

At the concentration of 100 µg/ml TiO 2 NPs, SCs showed a spindle-like shape, with very elongated cytoplasmic protrusions, typical of a cellular stress-associated condition, by the end of the first ...