to the devastating and often fatal syndrome of meningococcal septic shock and purpura fulminans. In the past few decades, considerable progress has been made in understanding the complex interaction ...

Complement is a complex innate immune surveillance system, playing a key role in defense against pathogens and in host homeostasis. The complement system is initiated by conformational changes in ...

Attempts to taper the prednisone quickly resulted in worsening abdominal pain and reappearance of the palpable purpura. Two months later, the patient's rash was cleared, and he is being monitored ...