This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

Cardiac macrophages in newborn mice promoted heart cell proliferation after injury, offering a potential approach to ...

该研究揭示了NGAL-MerTK通路在心肌修复中的关键作用，为心梗治疗提供了新靶点。 当心脏遭遇心肌梗死（MI）的致命打击后，中性粒细胞迅速释放的中性粒细胞明胶酶相关脂钙蛋白（NGAL）扮演了意想不到的修复指挥官角色。通过精妙的冠状动脉结扎小鼠模型 ...

The researchers found the ability of macrophages to engulf dying cells was enhanced in newborn mice due to increased expression of MerTK, a receptor that recognizes dying cells. Therefore ...

Flow cytometry analysis revealed that those with lympho-myeloid or diffuse-myeloid pathotypes showed comparable enrichment of two distinct synovial tissue macrophage populations (MerTK pos CD206 ...