肠易激综合征（IBS）与昼夜节律紊乱关系密切。为探究其内在机制，研究人员构建小鼠昼夜节律紊乱模型，发现该模型出现 IBS 样特征，肠道菌群组成和代谢也发生改变。这为理解 IBS 发病机制提供新视角。

There is no single technology to measure the entire metabolome. To address this, a wide variety of approaches, biological fluids, analytical platforms and statistical methods have been proposed to ...

GO 分类和 KEGG 富集分析 GO 分类分析将 DEGs 的功能分为生物过程、细胞成分和分子功能三大类，其中多个 GO term 与干旱胁迫耐受性和响应密切相关。KEGG 富集分析发现，不同比较组中富集的 KEGG 途径有所不同，表明耐旱和敏感幼苗在干旱胁迫下激活的分子响应途径 ...

The microbiome field is constantly providing insight on various health-related properties elicited by the commensals that inhabit their mammalian hosts. Harnessing the potential of these commensals ...

To determine functional hierarchies and their corresponding relative abundances, the gene catalog was aligned to the Kyoto Encyclopedia of Genes and Genomes (KEGG) database (v2018.01) using DIAMOND.

Methods:: Hyperlipidemic rats were induced by a high-fat diet (HFD) and treated with CSE. Serum, liver, and fecal samples were analyzed through biochemical assays, histopathological examination, 16S ...

Dana Schulz is an experienced editor, writer, and content strategist who is just as likely to be crunching the ... We offer the most up-to-date information from top experts, new research, and health ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cells change their metabolic profiles in ...